Inhibition of Cancer Cell Migration by Multiwalled Carbon Nanotubes | Zendy

GarcíaHevia Lorena | Zendy; Valiente Rafael | Zendy; FernándezLuna José L. | Zendy; Flahaut Emmanuel | Zendy; RodríguezFernández Lidia | Zendy; Villegas Juan C. | Zendy; González Jesús | Zendy; Fanarraga Mónica L. | Zendy

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Inhibition of Cancer Cell Migration by Multiwalled Carbon Nanotubes

Author(s) -

GarcíaHevia Lorena,

Valiente Rafael,

FernándezLuna José L.,

Flahaut Emmanuel,

RodríguezFernández Lidia,

Villegas Juan C.,

González Jesús,

Fanarraga Mónica L.

Publication year - 2015

Publication title -

advanced healthcare materials

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.288

H-Index - 90

eISSN - 2192-2659

pISSN - 2192-2640

DOI - 10.1002/adhm.201500252

Subject(s) - materials science , nanotechnology , carbon nanotube , cancer cell , cancer , carbon fibers , medicine , composite material , composite number

Inhibiting cancer cell migration and infiltration to other tissues makes the difference between life and death. Multiwalled carbon nanotubes (MWCNTs) display intrinsic biomimetic properties with microtubules, severely interfering with the function of these protein filaments during cell proliferation, triggering cell death. Here it is shown MWCNTs disrupt the centrosomal microtubule cytoskeletal organization triggering potent antimigratory effects in different cancer cells.

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