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Dynamic Nano‐Interfaces Enable Harvesting of Functional 3D‐Engineered Tissues
Author(s) -
Nishiguchi Akihiro,
Matsusaki Michiya,
Miyagawa Shigeru,
Sawa Yoshiki,
Akashi Mitsuru
Publication year - 2015
Publication title -
advanced healthcare materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.288
H-Index - 90
eISSN - 2192-2659
pISSN - 2192-2640
DOI - 10.1002/adhm.201500065
Subject(s) - materials science , regenerative medicine , nanotechnology , tissue engineering , nano , substrate (aquarium) , wetting , biomedical engineering , stem cell , microbiology and biotechnology , engineering , composite material , biology , ecology
Functional 3D‐engineered tissues are successfully harvested from a substrate using stimuli‐responsive hydrogel films with dynamic nano‐interface. The dynamic wettability control at the interfaces allows cellular detachment, leading to tissue harvesting without serious damage and remaining polymers. This method can be applied to various types of organs and used for tissue transplantation in regenerative medicine.