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Surface Charge Regulation of Osteogenic Differentiation of Mesenchymal Stem Cell on Polarized Ferroelectric Crystal Substrate
Author(s) -
Li Jianhua,
Mou Xiaoning,
Qiu Jichuan,
Wang Shu,
Wang Dongzhou,
Sun Dehui,
Guo Weibo,
Li Deshuai,
Kumar Anil,
Yang Xuebin,
Li Aixue,
Liu Hong
Publication year - 2015
Publication title -
advanced healthcare materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.288
H-Index - 90
eISSN - 2192-2659
pISSN - 2192-2640
DOI - 10.1002/adhm.201500032
Subject(s) - wafer , ferroelectricity , mesenchymal stem cell , lithium niobate , substrate (aquarium) , stem cell , materials science , nanotechnology , crystal (programming language) , microbiology and biotechnology , computer science , optoelectronics , biology , ecology , dielectric , programming language
Polarized ferroelectric crystal lithium niobate wafers with different cuts are selected to offer differently charged surfaces. By induction of the mesenchymal stem cells differentiation into osteoblasts on different charged surfaces, the specific osteogenic‐associated markers are assessed and the results illustrate that the positively charged wafer surface enhances rBMMSCs osteogenic differentiation.

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