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Silk‐Based Biomaterials in Biomedical Textiles and Fiber‐Based Implants
Author(s) -
Li Gang,
Li Yi,
Chen Guoqiang,
He Jihuan,
Han Yifan,
Wang Xiaoqin,
Kaplan David L.
Publication year - 2015
Publication title -
advanced healthcare materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.288
H-Index - 90
eISSN - 2192-2659
pISSN - 2192-2640
DOI - 10.1002/adhm.201500002
Subject(s) - biocompatibility , nanotechnology , biomaterial , biocompatible material , silk , biomedical engineering , materials science , engineering , composite material , metallurgy
Biomedical textiles and fiber‐based implants (BTFIs) have been in routine clinical use to facilitate healing for nearly five decades. Amongst the variety of biomaterials used, silk‐based biomaterials (SBBs) have been widely used clinically viz. sutures for centuries and are being increasingly recognized as a prospective material for biomedical textiles. The ease of processing, controllable degradability, remarkable mechanical properties and biocompatibility have prompted the use of SBBs for various BTFIs for extracorporeal implants, soft tissue repair, healthcare/hygiene products and related needs. The present Review focuses on BTFIs from the perspective of types and physical and biological properties, and this discussion is followed with an examination of the advantages and limitations of BTFIs from SBBs. The Review covers progress in surface coatings, physical and chemical modifications of SBBs for BTFIs and identifies future needs and opportunities for the further development for BTFIs using SBBs.