z-logo
Premium
Drug Delivery: Nanoengineered Particles for Enhanced Intra‐Articular Retention and Delivery of Proteins (Adv. Healthcare Mater. 10/2014)
Author(s) -
Singh Ankur,
Agarwal Rachit,
DiazRuiz Carlos A.,
Willett Nick J.,
Wang Peiyi,
Lee L. Andrew,
Wang Qian,
Guldberg Robert E.,
García Andrés J.
Publication year - 2014
Publication title -
advanced healthcare materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.288
H-Index - 90
eISSN - 2192-2659
pISSN - 2192-2640
DOI - 10.1002/adhm.201470051
Subject(s) - drug delivery , drug , materials science , medicine , pharmacology , biomedical engineering , nanotechnology
Localized intra‐articular delivery of anti‐inflammatory proteins can reduce inflammation in osteoarthritis but poses a challenge because of rapid clearance within few hours of injection. On page 1562, A. J. García and co‐workers report a new class of polymer that forms self‐assembled nanoparticles with therapeutic proteins for prolonged retention in intra‐articular joint spaces compared to bolus protein doses.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here