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Nanobiotechnology Promotes Noninvasive High‐Intensity Focused Ultrasound Cancer Surgery
Author(s) -
Chen Yu,
Chen Hangrong,
Shi Jianlin
Publication year - 2015
Publication title -
advanced healthcare materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.288
H-Index - 90
eISSN - 2192-2659
pISSN - 2192-2640
DOI - 10.1002/adhm.201400127
Subject(s) - nanobiotechnology , high intensity focused ultrasound , cancer surgery , ultrasound , cancer , intensity (physics) , medicine , biomedical engineering , nanotechnology , materials science , radiology , nanoparticle , optics , physics
The successful cancer eradication in a noninvasive manner is the ultimate objective in the fight against cancer. As a “bloodless scalpel,” high‐intensity focused ultrasound (HIFU) is regarded as one of the most promising and representative noninvasive therapeutic modalities for cancer surgery. However, large‐scale clinical applications of HIFU are still in their infancy because of critical efficiency and safety issues which remain to be solved. Fortunately, recently developed nanobiotechnology provides an alternative efficient approach to improve such important issues in HIFU, especially for cancer therapy. This Research News presents the very recent exciting progresses on the elaborate design and fabrication of organic, inorganic, and organic/inorganic hybrid nanoparticles for enhancing the HIFU ablation efficiency against tumor tissues. It is highly expected that this Research News can arouse more extensive research enthusiasm on the development of functional nanomaterials for highly efficient HIFU‐based synergistic therapy, which will give a promising noninvasive therapeutic modality for the successful cancer therapy with minimal damage to surrounding normal tissues, due to the noninvasive and site‐specific therapeutic features of HIFU.