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Stimuli‐Responsive Materials: The Role of Electrostatics and Temperature on Morphological Transitions of Hydrogel Nanostructures Self‐Assembled by Peptide Amphiphiles Via Molecular Dynamics Simulations (Adv. Healthcare Mater. 10/2013)
Author(s) -
Fu Iris W.,
Markegard Cade B.,
Chu Brian K.,
Nguyen Hung D.
Publication year - 2013
Publication title -
advanced healthcare materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.288
H-Index - 90
eISSN - 2192-2659
pISSN - 2192-2640
DOI - 10.1002/adhm.201370049
Subject(s) - materials science , nanostructure , molecular dynamics , nanotechnology , nanofiber , amphiphile , drug delivery , regenerative medicine , peptide , micelle , nanoscopic scale , tissue engineering , electrostatics , dynamics (music) , biophysics , polymer , biomedical engineering , chemistry , copolymer , computational chemistry , physics , composite material , medicine , biochemistry , biology , aqueous solution , cell , acoustics
Peptide amphiphiles self‐assemble into nanostructures as either cylindrical nanofibers or spherical micelles in response to specific physiological stimuli. Such morphological transition is captured by large‐scale molecular dynamics simulations in examining spontaneous selfassembly starting from random configurations. On page 1388 , the simulation study by Hung D. Nguyen and co‐workers can potentially aid the design and development of bio‐inspired materials for drug delivery, diagnostic medicine, tissue engineering, and regenerative medicine.