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Cell Patterning: Patterned Three‐Dimensional Encapsulation of Embryonic Stem Cells using Dielectrophoresis and Stereolithography (Adv. Healthcare Mater. 3/2013)
Author(s) -
Bajaj Piyush,
Marchwiany Daniel,
Duarte Carlos,
Bashir Rashid
Publication year - 2013
Publication title -
advanced healthcare materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.288
H-Index - 90
eISSN - 2192-2659
pISSN - 2192-2640
DOI - 10.1002/adhm.201370012
Subject(s) - stereolithography , dielectrophoresis , materials science , nanotechnology , tissue engineering , self healing hydrogels , ethylene glycol , stem cell , biomedical engineering , embryonic stem cell , cell encapsulation , microbiology and biotechnology , chemistry , composite material , polymer chemistry , chemical engineering , microfluidics , engineering , biology , biochemistry , gene
The integration of dielectrophoresis (DEP) with stereolithography (SL) apparatus for the spatial patterning of cells on custom‐made gold micro‐electrodes is reported by Rashid Bashir and co‐workers on page 450 . After patterning, the cells are encapsulated in poly (ethylene glycol) diacrylate (PEGDA) hydrogels of different stiffnesses. This robust and flexible in vitro platform can enable various applications in stem cell differentiation and tissue engineering by mimicking elements of the native 3D in vivo cellular micro‐environment.