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Ultrasound‐Triggered Regulation of Blood Glucose Levels Using Injectable Nano‐Network
Author(s) -
Di Jin,
Price Jennifer,
Gu Xiao,
Jiang Xiaoning,
Jing Yun,
Gu Zhen
Publication year - 2014
Publication title -
advanced healthcare materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.288
H-Index - 90
eISSN - 2192-2659
pISSN - 2192-2640
DOI - 10.1002/adhm.201300490
Subject(s) - in vivo , insulin , computer science , in vitro , ultrasound , medicine , chemistry , biology , biochemistry , microbiology and biotechnology , radiology
The integration of an injectable insulin‐encapsulated nano‐network with a focused ultrasound system (FUS) can remotely regulate insulin release both in vitro and in vivo. A single subcutaneous injection of the nano‐network with intermittent FUS administration facilitates reduction of the blood glucose levels in type 1 diabetic mice for up to 10 d.