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Carbon‐Nanotube‐Modified Electrodes for Highly Efficient Acute Neural Recording
Author(s) -
Shin Jung Hwal,
Kim Guk Bae,
Lee Eun Joo,
An Taechang,
Shin Kumjae,
Lee Seung Eun,
Choi WooSeok,
Lee Sukchan,
Latchoumane Charles,
Shin HeeSup,
Lim Geunbae
Publication year - 2014
Publication title -
advanced healthcare materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.288
H-Index - 90
eISSN - 2192-2659
pISSN - 2192-2640
DOI - 10.1002/adhm.201300183
Subject(s) - microelectrode , tungsten , carbon nanotube , materials science , electrode , neural activity , signal (programming language) , nanotechnology , multielectrode array , biomedical engineering , computer science , chemistry , neuroscience , medicine , metallurgy , biology , programming language
Microelectrodes are widely used for monitoring neural activities in various neurobiological studies. The size of the neural electrode is an important factor in determining the signal‐to‐noise ratio (SNR) of recorded neural signals and, thereby, the recording sensitivity. Here, it is demonstrated that commercial tungsten microelectrodes can be modified with carbon nanotubes (CNTs), resulting in a highly sensitive recording ability. The impedance with the respect to surface area of the CNT‐modified electrodes (CNEs) is much less than that of tungsten microelectrodes because of their large electrochemical surface area (ESA). In addition, the noise level of neural signals recorded by CNEs is significantly less. Thus, the SNR is greater than that obtained using tungsten microelectrodes. Importantly, when applied in a mouse brain in vivo, the CNEs can detect action potentials five times more efficiently than tungsten microelectrodes. This technique provides a significant advance in the recording of neural signals, especially in brain regions with sparse neuronal densities.