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A Highly Efficient Colorimetric Immunoassay Using a Nanocomposite Entrapping Magnetic and Platinum Nanoparticles in Ordered Mesoporous Carbon
Author(s) -
Kim Moon Il,
Ye Youngjin,
Woo MinAh,
Lee Jinwoo,
Park Hyun Gyu
Publication year - 2014
Publication title -
advanced healthcare materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.288
H-Index - 90
eISSN - 2192-2659
pISSN - 2192-2640
DOI - 10.1002/adhm.201300100
Subject(s) - nanocomposite , immunoassay , nanotechnology , nanoparticle , materials science , mesoporous material , magnetic nanoparticles , ultrashort pulse , chemistry , organic chemistry , medicine , physics , laser , antibody , optics , immunology , catalysis
Nanocomposite to achieve ultrafast immunoassay : A new synergistically integrated nanocomposite consisting of magnetic and platinum nanoparticles, simultaneously entrapped in mesoporous carbon, is developed as a promising enzyme mimetic candidate to achieve ultrafast colorimetric immunoassays. Using new assay system, clinically important target molecules, such as human epidermal growth factor receptor 2 (HER2) and diarrhea‐causing rotavirus, can be detected in only 3 min at room temperature with high specificity and sensitivity.