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Functional Living Biointerphases
Author(s) -
Saadeddin Anas,
RodrigoNavarro Aleixandre,
Monedero Vicente,
Rico Patricia,
Moratal David,
GonzálezMartín María Luisa,
Navarro David,
García Andrés J.,
SalmerónSánchez Manuel
Publication year - 2013
Publication title -
advanced healthcare materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.288
H-Index - 90
eISSN - 2192-2659
pISSN - 2192-2640
DOI - 10.1002/adhm.201200473
Subject(s) - medicine
Lactococcus lactis is modified to express a fibronectin fragment (FNIII 7‐10 ) as a membrane protein . This interphase, based on a living system, can be further exploited to provide spatio‐temporal factors to direct cell function at the material interface. This approach establishes a new paradigm in biomaterial surface functionalization for biomedical applications.