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Tunable Mechanical Properties of Ultrasmall Peptide Hydrogels by Crosslinking and Functionalization to Achieve the 3D Distribution of Cells
Author(s) -
Seow Wei Yang,
Hauser Charlotte A. E.
Publication year - 2013
Publication title -
advanced healthcare materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.288
H-Index - 90
eISSN - 2192-2659
pISSN - 2192-2640
DOI - 10.1002/adhm.201200463
Subject(s) - self healing hydrogels , biocompatible material , peptide , surface modification , disulfide bond , conjugated system , materials science , nanotechnology , computer science , polymer science , combinatorial chemistry , chemistry , polymer chemistry , chemical engineering , polymer , biomedical engineering , engineering , composite material , biochemistry
A disulfide‐crosslinked hydrogel made from ultrasmall peptides is introduced . Crosslinked gels are more elastic and better able to maintain shape integrity. Using facile chemistry, RGD (or other bioactive signals) can be conjugated onto the peptide fibers. Gels formed are biocompatible and support the three‐dimensional distribution of cells.