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Triggered Drug Release from Superhydrophobic Meshes using High‐Intensity Focused Ultrasound
Author(s) -
Yohe Stefan T.,
Kopechek Jonathan A.,
Porter Tyrone M.,
Colson Yolonda L.,
Grinstaff Mark W.
Publication year - 2013
Publication title -
advanced healthcare materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.288
H-Index - 90
eISSN - 2192-2659
pISSN - 2192-2640
DOI - 10.1002/adhm.201200381
Subject(s) - polygon mesh , drug delivery , high intensity focused ultrasound , computer science , visualization , layer (electronics) , ultrasound , materials science , nanotechnology , computer graphics (images) , artificial intelligence , physics , acoustics
Application of high‐intensity focused ultrasound to drug‐loaded superhydrophobic meshes affords triggered drug release by displacing an entrapped air layer. The air layer within the superhydrophobic meshes is characterized using direct visualization and B‐mode imaging. Drug‐loaded superhydrophobic meshes are cytotoxic in an in vitro assay after ultrasound treatment.