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Ultrasmall Manganese Ferrite Nanoparticles as Positive Contrast Agent for Magnetic Resonance Imaging
Author(s) -
Li Zhen,
Wang Shu Xia,
Sun Qiao,
Zhao Hong Li,
Lei Hao,
Lan Min Bo,
Cheng Zhen Xiang,
Wang Xiao Lin,
Dou Shi Xue,
Max Lu Gao Qing
Publication year - 2013
Publication title -
advanced healthcare materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.288
H-Index - 90
eISSN - 2192-2659
pISSN - 2192-2640
DOI - 10.1002/adhm.201200340
Subject(s) - materials science , magnetic resonance imaging , nanoparticle , manganese , nuclear magnetic resonance , contrast (vision) , ferrite (magnet) , magnetic nanoparticles , nanotechnology , medicine , optics , composite material , metallurgy , radiology , physics
Reducing ferromagnetic particle size is an important strategy to improve their positive effect on imaging through the suppression of their negative effect, demonstrated by ultrasmall manganese ferrite nanoparticles prepared from an environmentally‐friendly aqueous route. These ultrasmall particles exhibit pronounced paramagnetic characteristics and nontoxicity, making them efficient T 1 ‐positive contrast agent and manganese contrast agents for manganese enhanced MRI.