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Electroresponsive Polymer–Carbon Nanotube Hydrogel Hybrids for Pulsatile Drug Delivery In Vivo
Author(s) -
Servant Ania,
Methven Laura,
Williams Rhodri P.,
Kostarelos Kostas
Publication year - 2013
Publication title -
advanced healthcare materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.288
H-Index - 90
eISSN - 2192-2659
pISSN - 2192-2640
DOI - 10.1002/adhm.201200193
Subject(s) - drug delivery , pulsatile flow , materials science , nanotechnology , carbon nanotube , in vivo , polymer , computer science , biomedical engineering , medicine , microbiology and biotechnology , composite material , cardiology , biology
Drug release triggered by an external non‐invasive stimulus is of great interest for the development of new drug delivery systems . The preparation of an electroresponsive multiwalled carbon nanotube/poly(methylacrylic acid) (MWNT/PMAA)‐based hybrid material is reported. The hydrogel hybrids achieve a controlled drug release upon the ON/OFF application of an electric field, giving rise to in vitro and in vivo pulsatile release profiles.