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Hybrid Conducting Polymer–Hydrogel Conduits for Axonal Growth and Neural Tissue Engineering
Author(s) -
Abidian Mohammad R.,
Daneshvar Eugene D.,
Egeland Brent M.,
Kipke Daryl R.,
Cederna Paul S.,
Urbanchek Melanie G.
Publication year - 2012
Publication title -
advanced healthcare materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.288
H-Index - 90
eISSN - 2192-2659
pISSN - 2192-2640
DOI - 10.1002/adhm.201200182
Subject(s) - pedot:pss , materials science , tissue engineering , agarose , fabrication , peripheral nerve , nerve guidance conduit , regeneration (biology) , biomedical engineering , conductive polymer , neural tissue engineering , polymer , nanotechnology , bridging (networking) , electrical conductor , composite material , anatomy , computer science , chemistry , medicine , computer network , alternative medicine , chromatography , pathology , biology , microbiology and biotechnology
Successfully and efficiently bridging peripheral nerve gaps without the use of autografts is a substantial clinical advance for peripheral nerve reconstructions. Novel templating methods for the fabrication of conductive hydrogel guidance channels for axonal regeneration are designed and developed. PEDOT is electrodeposited inside the lumen to create fully coated‐PEDOT agarose conduits and partially coated‐PEDOT agarose conduits.