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A Hydrophobic Dye‐Encapsulated Nano‐Hybrid as an Efficient Fluorescent Probe for Living Cell Imaging
Author(s) -
Chang Shu,
Wu Xumeng,
Li Yongsheng,
Niu Dechao,
Ma Zhi,
Zhao Wenru,
Gu Jinlou,
Dong Wenjie,
Ding Feng,
Zhu Weihong,
Shi Jianlin
Publication year - 2012
Publication title -
advanced healthcare materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.288
H-Index - 90
eISSN - 2192-2659
pISSN - 2192-2640
DOI - 10.1002/adhm.201200144
Subject(s) - amphiphile , fluorescence , copolymer , water soluble , nano , nanotechnology , silane , aqueous solution , materials science , quantum yield , aqueous medium , block (permutation group theory) , information storage , computer science , chemistry , organic chemistry , polymer , optics , information retrieval , physics , geometry , mathematics , composite material
Water‐soluble hydrophobic‐dye@nano‐hybrids (DPN@NHs) with extraordinarily enhanced fluorescent performance were fabricated by encapsulating the hydrophobic dye molecules into the core of the hybrid nanospheres based on the self‐assembly of amphiphilic block copolymers followed by shell cross‐linking using 3‐mercaptopropyltrimethoxy‐silane. The DPN@NHs are 50 nm in size, are monodispersed in aqueous solution and have a quantum yield enhanced by 30 times.