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Rational Molecular Design of Complementary Self‐Assembling Peptide Hydrogels
Author(s) -
Kyle Stuart,
Felton Susan H,
McPherson Michael J.,
Aggeli Amalia,
Ingham Eileen
Publication year - 2012
Publication title -
advanced healthcare materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.288
H-Index - 90
eISSN - 2192-2659
pISSN - 2192-2640
DOI - 10.1002/adhm.201200047
Subject(s) - self healing hydrogels , rational design , peptide , self assembling peptide , biomaterial , nanotechnology , materials science , self assembly , biophysics , chemistry , biochemistry , polymer chemistry , biology
Rational molecular design of self‐ assembling peptide‐based materials that spontaneously form self‐supporting hydrogels shows potential in many healthcare applications. Binary peptides based on complementary charged sequences are developed, and the use of biophysical analysis and cell‐based studies highlights that the charged interactions can influence the properties of peptide materials and ultimately affect biomaterial applications.