Premium
Biomineralization‐Based Virus Shell‐Engineering: Towards Neutralization Escape and Tropism Expansion
Author(s) -
Wang Xiaoyu,
Deng Yongqiang,
Li Shihua,
Wang Guangchuan,
Qin Ede,
Xu Xurong,
Tang Ruikang,
Qin Chengfeng
Publication year - 2012
Publication title -
advanced healthcare materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.288
H-Index - 90
eISSN - 2192-2659
pISSN - 2192-2640
DOI - 10.1002/adhm.201200034
Subject(s) - biomineralization , neutralization , virus , shell (structure) , biocompatible material , tissue engineering , nanotechnology , materials science , virology , biology , chemical engineering , engineering , biomedical engineering , composite material
Biomineralization‐based virus shell‐engineering (BVSE) is a potential surface modification strategy to afford a biocompatible and biodegradable calcium phosphate (CaPi) shell onto single virus, allowing development of Trojan virus with enhanced infection, expanded tropism and neutralization escape, which open up the multiple applications of virus in biomedicines and materials.