Magnetic Nanocomposite Sol–Gel Systems for Remote Controlled Drug Release | Zendy

Hawkins Ashley M. | Zendy; Bottom Chelsie E. | Zendy; Liang Zhi | Zendy; Puleo David A. | Zendy; Hilt J. Zach | Zendy

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Magnetic Nanocomposite Sol–Gel Systems for Remote Controlled Drug Release

Author(s) -

Hawkins Ashley M.,

Bottom Chelsie E.,

Liang Zhi,

Puleo David A.,

Hilt J. Zach

Publication year - 2012

Publication title -

advanced healthcare materials

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.288

H-Index - 90

eISSN - 2192-2659

pISSN - 2192-2640

DOI - 10.1002/adhm.201100013

Subject(s) - materials science , drug delivery , copolymer , polymer , nanotechnology , chemical engineering , sol gel , nanocomposite , phase transition , phase (matter) , biomedical engineering , composite material , chemistry , organic chemistry , medicine , engineering , physics , quantum mechanics

The remote heating of iron oxide nanoparticles in an alternating magnetic field is used to drive a thermoresponsive sol‐gel block copolymer, Pluronic® F‐127, through the upper phase transition temperature. This phase change triggers an accelerated release rate of a model drug. Actuation and return to baseline levels are demonstrated for multiple AMF doses.

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