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Polymeric Nanoneedle Arrays Mediate Stiffness‐Independent Intracellular Delivery (Adv. Funct. Mater. 3/2022)
Author(s) -
Yoh Hao Zhe,
Chen Yaping,
Aslanoglou Stella,
Wong Sherman,
Trifunovic Zlatan,
Crawford Simon,
Lestrell Esther,
Priest Craig,
Alba Maria,
Thissen Helmut,
Voelcker Nicolas H.,
Elnathan Roey
Publication year - 2022
Publication title -
advanced functional materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.069
H-Index - 322
eISSN - 1616-3028
pISSN - 1616-301X
DOI - 10.1002/adfm.202270021
Subject(s) - nanoneedle , materials science , nanotechnology , polystyrene , petri dish , fabrication , intracellular , nanostructure , polymer , microbiology and biotechnology , composite material , biology , medicine , alternative medicine , pathology , genetics
Polymeric Nanoneedle Arrays In article number 2104828, Yaping Chen, Nicolas H. Voelcker, Roey Elnathan, and co‐workers demonstrate the fabrication of relatively low‐cost and high throughput polymeric nanoneedles from cell culture polystyrene. The nanoneedles with precise geometry are imprinted directly on polystyrene from the cell culture petri dish via nanoimprint lithography. The nanoneedles arrays can precisely manipulate cellular processes and mediate intracellular delivery in mammalian cells. This presents opportunities for novel integration of nanostructures into traditional polymeric cell cultureware.