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Microneedle Patch Delivery: Microneedle Patch Delivery of Capsaicin‐Containing α‐Lactalbumin Nanomicelles to Adipocytes Achieves Potent Anti‐Obesity Effects (Adv. Funct. Mater. 20/2021)
Author(s) -
Bao Cheng,
Li Zekun,
Liang Shuang,
Hu Yulin,
Wang Xiaoyu,
Fang Bing,
Wang Pengjie,
Chen Shanan,
Li Yuan
Publication year - 2021
Publication title -
advanced functional materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.069
H-Index - 322
eISSN - 1616-3028
pISSN - 1616-301X
DOI - 10.1002/adfm.202170144
Subject(s) - capsaicin , adipose tissue , drug delivery , materials science , lipogenesis , pharmacology , micelle , subcutaneous fat , adipogenesis , biophysics , biomedical engineering , medicine , nanotechnology , chemistry , biology , receptor , aqueous solution
In article number 2011130, Yuan Li and co‐workers present a minimally invasive anti‐obesity treatment system that supports local targeting of adipose tissues. The microneedles successfully deliver pepper sourced compound‐capsaicin (Cap) loaded a‐lactalbumin micelles into subcutaneous adipocytes, promoting the “burning” anti‐lipogenesis effect of fat cells by Cap. This delivery system selectively targets adipose and could represent a non‐invasive approach for treating obesity.