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Cyber‐Physical Watermarking with Inkjet Edible Bioprinting
Author(s) -
Jeon HeeJae,
Leem Jung Woo,
Ji Yuhyun,
Park Sang Mok,
Park Jongwoo,
Kim KeeYoung,
Kim SeongWan,
Kim Young L.
Publication year - 2022
Publication title -
advanced functional materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.069
H-Index - 322
eISSN - 1616-3028
pISSN - 1616-301X
DOI - 10.1002/adfm.202112479
Subject(s) - digital watermarking , robustness (evolution) , counterfeit , computer science , computer security , authentication (law) , materials science , artificial intelligence , internet privacy , image (mathematics) , biochemistry , chemistry , political science , law , gene
Counterfeit medicines are a fundamental healthcare problem, threatening patient safety and public health as well as causing economic damage. Online pharmacies and the ongoing pandemic have promoted medicine counterfeiting. However, the existing anticounterfeit methods are limited because of material toxicity, low security, and complicated fabrication. Here a dosage‐level security method is introduced that combines digital watermarking and physical printing at the material level. A set of requirements is designed to ensure the edibility, printability, imperceptibility, and robustness of cyber‐physical watermarking. An inkjet printer using safe food coloring is adapted to print a watermarked image on a recombinant luminescent silk protein taggant to enhance attack resistance. Machine learning of color accuracy recovers unavoidable color distortions during printing and acquisition, allowing robust smartphone readability. An edible watermarked taggant affixed to each individual medicine can offer anticounterfeit and authentication features at the dosage level, empowering every patient to aid in abating illicit medicines.