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Wound Healing: Carbon Dots Induce Epithelial‐Mesenchymal Transition for Promoting Cutaneous Wound Healing via Activation of TGF‐β/p38/Snail Pathway (Adv. Funct. Mater. 43/2020)
Author(s) -
Wang Zilin,
Liu Lili,
Bu Wenhuan,
Zheng Mengdan,
Jin Nianqiang,
Zhang Kai,
Xu Xiaowei,
Zhou Ding,
Yang Bai,
Sun Hongchen
Publication year - 2020
Publication title -
advanced functional materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.069
H-Index - 322
eISSN - 1616-3028
pISSN - 1616-301X
DOI - 10.1002/adfm.202070283
Subject(s) - snail , materials science , wound healing , mesenchymal stem cell , scars , epithelial–mesenchymal transition , transforming growth factor , motility , microbiology and biotechnology , biocompatibility , nanotechnology , cancer research , medicine , immunology , biochemistry , biology , pathology , downregulation and upregulation , ecology , gene , metallurgy
In article number 2004886, Xiaowei Xu, Ding Zhou, Hongchen Sun, and co‐workers synthesize carbon dots with excellent biocompatibility via microwave‐assisted heating of ascorbic acid and polyethyleneimine. The synthesized carbon dots can induce the epithelial‐mesenchymal transition process by activating the transforming growth factor‐β/p‐38 mitogen‐activated kinase/Snail signaling pathway, leading to increased cell motility, and thus promote full‐thickness cutaneous wound healing with fewer scars.