Islet Transplantation: A Collagen Based Cryogel Bioscaffold that Generates Oxygen for Islet Transplantation (Adv. Funct. Mater. 15/2020) | Zendy

Razavi Mehdi | Zendy; Primavera Rosita | Zendy; Kevadiya Bhavesh D. | Zendy; Wang Jing | Zendy; Buchwald Peter | Zendy; Thakor Avnesh S. | Zendy

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Islet Transplantation: A Collagen Based Cryogel Bioscaffold that Generates Oxygen for Islet Transplantation (Adv. Funct. Mater. 15/2020)

Author(s) -

Razavi Mehdi,

Primavera Rosita,

Kevadiya Bhavesh D.,

Wang Jing,

Buchwald Peter,

Thakor Avnesh S.

Publication year - 2020

Publication title -

advanced functional materials

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 6.069

H-Index - 322

eISSN - 1616-3028

pISSN - 1616-301X

DOI - 10.1002/adfm.202070099

Subject(s) - islet , transplantation , materials science , biomedical engineering , oxygen , pancreatic islets , matrix (chemical analysis) , biophysics , microbiology and biotechnology , medicine , chemistry , surgery , biology , composite material , insulin , organic chemistry

In article number 1902463, Avnesh S. Thakor and co‐workers design a macroporous collagen‐based cryogel bioscaffold that can accommodate transplanted pancreatic islets. Calcium peroxide, which generates a steady supply of oxygen, is then incorporated into the matrix of this bioscaffold. This clinically translatable platform improves the function and viability of transplanted islets until they can establish a new blood supply, and hence their own source of oxygen, following transplantation.

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