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Biomimetic Nanomaterial Strategies for Virus Targeting: Antiviral Therapies and Vaccines
Author(s) -
Jackman Joshua A.,
Yoon Bo Kyeong,
Ouyang Lei,
Wang Nan,
Ferhan Abdul Rahim,
Kim Jaeyun,
Majima Tetsuro,
Cho NamJoon
Publication year - 2021
Publication title -
advanced functional materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.069
H-Index - 322
eISSN - 1616-3028
pISSN - 1616-301X
DOI - 10.1002/adfm.202008352
Subject(s) - nanotechnology , covid-19 , nanomaterials , virus , pandemic , virology , materials science , medicine , disease , infectious disease (medical specialty) , pathology
The ongoing coronavirus disease 2019 (COVID‐19) pandemic highlights the importance of developing effective virus targeting strategies to treat and prevent viral infections. Since virus particles are nanoscale entities, nanomaterial design strategies are ideally suited to create advanced materials that can interact with and mimic virus particles. In this progress report, the latest advances in biomimetic nanomaterials are critically discussed for combating viral infections, including in the areas of nanomaterial‐enhanced viral replication inhibitors, biomimetic virus particle capture schemes, and nanoparticle vaccines. Particular focus is placed on nanomaterial design concepts and material innovations that can be readily developed to thwart future viral threats. Pertinent nanomaterial examples from the COVID‐19 situation are also covered along with discussion of human clinical trial efforts underway that might lead to next‐generation antiviral therapies and vaccines.