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3D Printed Tissues: 3D Printed Cartilage‐Like Tissue Constructs with Spatially Controlled Mechanical Properties (Adv. Funct. Mater. 51/2019)
Author(s) -
Melo Bruna A. G.,
Jodat Yasamin A.,
Mehrotra Shreya,
Calabrese Michelle A.,
Kamperman Tom,
Mandal Biman B.,
Santana Maria H. A.,
Alsberg Eben,
Leijten Jeroen,
Shin Su Ryon
Publication year - 2019
Publication title -
advanced functional materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.069
H-Index - 322
eISSN - 1616-3028
pISSN - 1616-301X
DOI - 10.1002/adfm.201970350
Subject(s) - materials science , cartilage , chondrogenesis , 3d printed , mesenchymal stem cell , biomedical engineering , 3d bioprinting , spheroid , nanotechnology , tissue engineering , composite material , anatomy , microbiology and biotechnology , cell culture , engineering , biology , genetics , medicine
In article number 1906330, Jeroen Leijten, Su Ryon Shin, and co‐workers develop 3D cartilage‐like tissue through local bioprinting of mesenchymal stem cell spheroids laden with soft and cell stimulating bioink within a mechanically robust hydrogel. This uncoupling of the micro and macro mechanical properties of the 3D printed construct allows it to possess both a chondrogenic microenvironment and the ability to withstand mechanical loads.