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Biomedical Applications: Gram‐Negative Bacteria Targeting Mediated by Carbohydrate–Carbohydrate Interactions Induced by Surface‐Modified Nanoparticles (Adv. Funct. Mater. 48/2019)
Author(s) -
Capeletti Larissa Brentano,
Oliveira Jessica Fernanda Affonso,
Loiola Lívia Mesquita Dias,
Galdino Flávia Elisa,
Silva Santos Denys Ewerton,
Soares Thereza Amélia,
Oliveira Freitas Raul,
Cardoso Mateus Borba
Publication year - 2019
Publication title -
advanced functional materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.069
H-Index - 322
eISSN - 1616-3028
pISSN - 1616-301X
DOI - 10.1002/adfm.201970325
Subject(s) - bacteria , materials science , adhesion , nanoparticle , nanotechnology , carbohydrate , nanomedicine , membrane , gram negative bacteria , biophysics , biochemistry , biology , escherichia coli , composite material , genetics , gene
In article number 1904216, Mateus Borba Cardoso and co‐workers demonstrate that nanoparticles fuctionalized with gluconamide moieties present selective targeting ability to Gram‐negative bacteria membranes and no significant toxicity to mammalian or red blood cells. In addition, gluconamide functionality also provides tunable antibiotic delivery abilities, high stability in complex biological media, and lack of non‐specific protein adhesion.