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Bioprinting: A Tumor‐on‐a‐Chip System with Bioprinted Blood and Lymphatic Vessel Pair (Adv. Funct. Mater. 31/2019)
Author(s) -
Cao Xia,
Ashfaq Ramla,
Cheng Feng,
Maharjan Sushila,
Li Jun,
Ying Guoliang,
Hassan Shabir,
Xiao Haiyan,
Yue Kan,
Zhang Yu Shrike
Publication year - 2019
Publication title -
advanced functional materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.069
H-Index - 322
eISSN - 1616-3028
pISSN - 1616-301X
DOI - 10.1002/adfm.201970217
Subject(s) - lymphatic system , lymphatic vessel , materials science , blood vessel , biomedical engineering , 3d bioprinting , microcirculation , nanotechnology , cancer , pathology , tissue engineering , medicine , metastasis
In article number 1807173, Yu Shrike Zhang and co‐workers report the development of an improved tumor‐on‐a‐chip model consisting of a bioprinted hollow, perfusable blood vessel for liquid delivery and a hollow, single end‐blinded lymphatic vessel for interstitial fluid draining, hosted in a 3D tumor microenvironment‐like hydrogel matrix. This model featuring the biomimetic local microcirculation exhibits well‐controlled transport of biomolecules and anti‐cancer drugs.