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Cancer Immunotherapy: Designing Bioinspired 2D MoSe 2 Nanosheet for Efficient Photothermal‐Triggered Cancer Immunotherapy with Reprogramming Tumor‐Associated Macrophages (Adv. Funct. Mater. 30/2019)
Author(s) -
He Lizhen,
Nie Tianqi,
Xia Xiaojun,
Liu Ting,
Huang Yanyu,
Wang Xiaojuan,
Chen Tianfeng
Publication year - 2019
Publication title -
advanced functional materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.069
H-Index - 322
eISSN - 1616-3028
pISSN - 1616-301X
DOI - 10.1002/adfm.201970210
Subject(s) - photothermal therapy , reprogramming , cancer immunotherapy , materials science , immunotherapy , nanosheet , cancer , cancer research , cytotoxic t cell , cancer cell , nanotechnology , cell , medicine , biology , in vitro , biochemistry
In article number 1901240, Tianfeng Chen and co‐workers design bioinspired 2D MoSe 2 nanosheets with high photothermal conversion efficiency to achieve efficient photothermal‐triggered cancer immunotherapy, by activating cytotoxic T lymphocytes, reprogramming tumor associated macrophages to a tumoricidal M1 phenotype, and inactivation of the PD‐1/PD‐L1 pathway to avoid immunologic escape.