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Nanobiointerfaces: Human Platelet Membrane Functionalized Microchips with Plasmonic Codes for Cancer Detection (Adv. Funct. Mater. 30/2019)
Author(s) -
Kumar Sumit,
Han JaeA,
Michael Issac J.,
Ki Dongyeob,
Sunkara Vijaya,
Park Juhee,
Gautam Shreedhar,
Ha Hong Koo,
Zhang Liangfang,
Cho YoonKyoung
Publication year - 2019
Publication title -
advanced functional materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.069
H-Index - 322
eISSN - 1616-3028
pISSN - 1616-301X
DOI - 10.1002/adfm.201970205
Subject(s) - materials science , platelet , nanotechnology , chip , microfluidic chip , membrane , extracellular vesicles , biomedical engineering , microfluidics , cancer cell , cancer detection , surface modification , optoelectronics , cancer , computer science , chemical engineering , medicine , chemistry , microbiology and biotechnology , telecommunications , engineering , biochemistry , biology
In article number 1902669, Yoon‐Kyoung Cho and co‐workers describe a microfluidic chip equipped with a platelet membrane‐cloaked surface, the “PLT‐Chip,” which takes advantage of the strong and specific interaction between platelets and cancer‐derived extracellular vesicles. The PLT‐Chip accurately detects cancer using ultra‐small volumes (1 µL) of patient's plasma samples, with high sensitivity.