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Polymeric Photosensitizers: Tumor‐Specific Aptamer‐Conjugated Polymeric Photosensitizer for Effective Endo‐Laparoscopic Photodynamic Therapy (Adv. Funct. Mater. 23/2019)
Author(s) -
Kim Jiyoung,
Park Wooram,
Kim Dahye,
Lee Eun Seong,
Lee Don Haeng,
Jeong Seok,
Park Jae Myung,
Na Kun
Publication year - 2019
Publication title -
advanced functional materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.069
H-Index - 322
eISSN - 1616-3028
pISSN - 1616-301X
DOI - 10.1002/adfm.201970159
Subject(s) - photosensitizer , photodynamic therapy , aptamer , conjugated system , materials science , cancer research , photochemistry , medicine , chemistry , polymer , biology , microbiology and biotechnology , organic chemistry , composite material
In article number 1900084 , Kun Na and co‐workers report a tumor‐specific aptamer‐conjugated polymeric photosensitizer (PS) to achieve an effective endo‐laparoscopic photodynamic therapy with minimal invasiveness for the treatment of gastrointestinal cancers. The tumor‐specific PS can not only accurately detect tumor tissue within a few minutes but also effectively treat the labeled tumor tissue by cytotoxic reactive oxygen species generation following laser irradiation.