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Medical Applications: Rapid and Long‐Term Glycemic Regulation with a Balanced Charged Immune‐Evasive Hydrogel in T1DM Mice (Adv. Funct. Mater. 19/2019)
Author(s) -
Zhang Jiamin,
Zhu Yingnan,
Song Jiayin,
Xu Tong,
Yang Jing,
Du Yan,
Zhang Lei
Publication year - 2019
Publication title -
advanced functional materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.069
H-Index - 322
eISSN - 1616-3028
pISSN - 1616-301X
DOI - 10.1002/adfm.201970130
Subject(s) - glycemic , immune system , materials science , artificial pancreas , insulin , islet , term (time) , diabetes mellitus , nanotechnology , self healing hydrogels , biomedical engineering , medicine , endocrinology , type 1 diabetes , immunology , polymer chemistry , physics , quantum mechanics
In article number 1900140 , Lei Zhang and co‐workers report an effective immune‐evasive hydrogel that can well accommodate islets and maintain their glucose‐responsive and insulin‐producing functions. This novel strategy can achieve dynamic, long‐term, stable regulation of blood glucose levels in diabetic mice and endow them with pancreas functionality after intraperitoneal implantation.