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Bioimaging: NIR‐II Excitable Conjugated Polymer Dots with Bright NIR‐I Emission for Deep In Vivo Two‐Photon Brain Imaging Through Intact Skull (Adv. Funct. Mater. 15/2019)
Author(s) -
Wang Shaowei,
Liu Jie,
Feng Guangxue,
Ng Lai Guan,
Liu Bin
Publication year - 2019
Publication title -
advanced functional materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.069
H-Index - 322
eISSN - 1616-3028
pISSN - 1616-301X
DOI - 10.1002/adfm.201970095
Subject(s) - materials science , conjugated system , skull , two photon excitation microscopy , in vivo , polymer , nanotechnology , optics , fluorescence , anatomy , medicine , physics , microbiology and biotechnology , biology , composite material
In article number 1808365 , Bin Liu and co‐workers report NIR‐II light (1200 nm) excitable single‐chain conjugated polymer dots with bright NIR‐I emission (peak at ≈725 nm and quantum yield of 20.6%) for deep in vivo two‐photon imaging of an intact brain. High contrast images clearly reveal brain vasculature structure through the intact skull with a large depth of 400 μm.