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Computationally Selected Epitopes: Integrated Approaches Toward High‐Affinity Artificial Protein Binders Obtained via Computationally Simulated Epitopes for Protein Recognition (Adv. Funct. Mater. 15/2019)
Author(s) -
Altintas Zeynep,
Takiden Aref,
Utesch Tillmann,
Mroginski Maria A.,
Schmid Bianca,
Scheller Frieder W.,
Süssmuth Roderich D.
Publication year - 2019
Publication title -
advanced functional materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.069
H-Index - 322
eISSN - 1616-3028
pISSN - 1616-301X
DOI - 10.1002/adfm.201970094
Subject(s) - epitope , materials science , biomarker , molecular recognition , nanotechnology , antibody , biochemistry , biology , chemistry , molecule , immunology , organic chemistry
In article number 1807332 , Zeynep Altintas and co‐workers combine computational and experimental studies to develop high affinity artificial protein binders by targeting a cancer biomarker. The artificial receptors show excellent affinity toward the protein marker, even superior to that of state‐of‐the‐art antibodies.