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Biomimetic Scaffolds: 3D Molecularly Functionalized Cell‐Free Biomimetic Scaffolds for Osteochondral Regeneration (Adv. Funct. Mater. 6/2019)
Author(s) -
Li Lan,
Li Jiayi,
Guo Jiamin,
Zhang Huikang,
Zhang Xin,
Yin Caiyun,
Wang Liming,
Zhu Yishen,
Yao Qingqiang
Publication year - 2019
Publication title -
advanced functional materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.069
H-Index - 322
eISSN - 1616-3028
pISSN - 1616-301X
DOI - 10.1002/adfm.201970036
Subject(s) - materials science , polycaprolactone , regeneration (biology) , biomedical engineering , osteoarthritis , cartilage , scaffold , coating , nanotechnology , polymer , composite material , anatomy , medicine , alternative medicine , pathology , biology , microbiology and biotechnology
In article number 1807356 , Yishen Zhu, Qingqiang Yao, and co‐workers develop a strategy to molecularly functionalize the self‐assembling peptide hydrogel (SAPH) FEFEFKFK onto 3D‐printed polycaprolactone (PCL) scaffolds, forming a reliable and stable coating layer. The prepared SAPH‐coated PCL scaffolds provide a superior performance for the regeneration of cartilage and subchondral bone simultaneously, offering a flexible strategy for osteochondral defects caused by osteoarthritis or acute trauma.