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Seaweed‐Derived Electrospun Nanofibrous Membranes for Ultrahigh Protein Adsorption
Author(s) -
Dou Xueyu,
Wang Qian,
Li Zhaoling,
Ju Junping,
Wang Shuang,
Hao Longyun,
Sui Kunyan,
Xia Yanzhi,
Tan Yeqiang
Publication year - 2019
Publication title -
advanced functional materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.069
H-Index - 322
eISSN - 1616-3028
pISSN - 1616-301X
DOI - 10.1002/adfm.201905610
Subject(s) - membrane , electrospinning , adsorption , materials science , protein adsorption , nanofiber , chemical engineering , porosity , polymer , nanotechnology , composite material , organic chemistry , chemistry , biochemistry , engineering
Construction of simple and efficient protein adsorption materials is extremely vital to satisfy the requirements of highly purified proteins in biopharmaceutical and biotechnological industries, yet remains challenging. Herein, a cost‐effective strategy to develop seaweed‐derived nanofibrous membranes (NFM) for ultrahigh protein adsorption is reported. Synergistic regulation by cosolvent of ethanol, nonionic surfactants of Triton X‐100, and polyethylene oxide (PEO 5000k ) is employed to realize electrospinning of seaweed‐derived sodium alginate (SA) nanofibers with higher alginate content of 98 wt% to date, and following water washing easily generates SA nanofibrous membranes (SA‐NFM) with excellent morphology. Benefiting from the nanoscale merit of large specific surface area and tortuously porous microstructure, SA‐NFM exhibit a high actual capacity of 1235 mg g −1 toward lysozyme, which far exceeds maximum value for the reported 2D membrane materials (710 mg g −1 ) and is about 20 times that of commercial membranes adsorbents (51 mg g −1 ). Higher dynamic capacity of 805 mg g −1 (gravity driven) is also realized to meet the demand of practical application. The SA‐NFM also possess outstanding reversibility and unique selectivity toward specific proteins. Herein, SA‐NFM represent a perfect candidate for next‐generation protein absorbents for fast and efficient bioseparation.