Premium
Regenerative Medicine: Multiphasic Collagen Scaffolds for Engineered Tissue Interfaces (Adv. Funct. Mater. 48/2018)
Author(s) -
Lausch Alexander J.,
Chong Lester C.,
Uludag Hasan,
Sone Eli D.
Publication year - 2018
Publication title -
advanced functional materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.069
H-Index - 322
eISSN - 1616-3028
pISSN - 1616-301X
DOI - 10.1002/adfm.201870343
Subject(s) - materials science , collagen fibril , connective tissue , biomedical engineering , regenerative medicine , anatomy , stem cell , microbiology and biotechnology , pathology , medicine , biology
In article number 1804730 , Eli D. Sone and co‐workers report on the development of biomimetic collagen scaffolds that incorporate bone‐like mineralized layers alongside unmineralized layers, resembling hard‐soft connective tissue interfaces. The boundary between mineralized and unmineralized layers is well defined, with unmineralized collagen fibrils intermingling with the mineralized layer to create mechanical interlock without need for adhesives.