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Tumor Imaging: Colorectal Cancer Diagnosis Using Enzyme‐Sensitive Ratiometric Fluorescence Dye and Antibody–Quantum Dot Conjugates for Multiplexed Detection (Adv. Funct. Mater. 4/2018)
Author(s) -
Park Youngrong,
Ryu YeonMi,
Wang Taejun,
Jung Yebin,
Kim Sohee,
Hwang Sekyu,
Park Joonhyuck,
Bae DongJun,
Kim Jaeil,
Moon Heejo,
Lim HyunSuk,
Kim SangYeob,
Chung Euiheon,
Kim Ki Hean,
Kim Sungjee,
Myung SeungJae
Publication year - 2018
Publication title -
advanced functional materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.069
H-Index - 322
eISSN - 1616-3028
pISSN - 1616-301X
DOI - 10.1002/adfm.201870026
Subject(s) - quantum dot , conjugate , fluorescence , materials science , colorectal cancer , naked eye , fluorescence lifetime imaging microscopy , microbiology and biotechnology , nanotechnology , cancer , optics , medicine , biology , physics , mathematics , mathematical analysis
Two imaging probes can be co‐used for colonoscopic diagnosis: a fluorescent probe that ratiometrically switches between two colors in response to λ‐glutamyltranspeptidase activity and an antibodyquantum dot probe. As shown by Ki Hean Kim, Sungjee Kim, Seung‐Jae Myung, and co‐workers in article number 1703450 , co‐application of two probes affords accurate visualization of early‐stage carcinomas that are not easily discernible with the naked eye.