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Cancer Therapy: A Multifunctional Nanoplatform against Multidrug Resistant Cancer: Merging the Best of Targeted Chemo/Gene/Photothermal Therapy (Adv. Funct. Mater. 45/2017)
Author(s) -
Cheng Wei,
Nie Junpeng,
Gao Nansha,
Liu Gan,
Tao Wei,
Xiao Xiaojun,
Jiang Lijuan,
Liu Zhigang,
Zeng Xiaowei,
Mei Lin
Publication year - 2017
Publication title -
advanced functional materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.069
H-Index - 322
eISSN - 1616-3028
pISSN - 1616-301X
DOI - 10.1002/adfm.201770270
Subject(s) - photothermal therapy , materials science , nanotechnology , in vivo , cancer , multiple drug resistance , mesoporous silica , cancer research , cancer therapy , nanoparticle , in vitro , medicine , drug resistance , mesoporous material , biology , biochemistry , microbiology and biotechnology , catalysis
In article number 1704135 , Gan Liu, Xiaowei Zeng, Lin Mei, and co‐workers fabricate a multifunctional nanoplatform against multidrug resistant cancer using targeted mesoporous silica nanoparticles. This nanoplatform tactfully integrates chemo‐ (DOX), Gene‐ (P‐gp siRNA) and photothermal (PDA layer) substances in one system. Both in vitro and in vivo antitumor experiments demonstrate the enhanced antitumor efficacy of the multifunctional nanoparticles.