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Cancer Therapy: Photo‐Induced Charge‐Variable Conjugated Polyelectrolyte Brushes Encapsulating Upconversion Nanoparticles for Promoted siRNA Release and Collaborative Photodynamic Therapy under NIR Light Irradiation (Adv. Funct. Mater. 44/2017)
Author(s) -
Zhao Hui,
Hu Wenbo,
Ma Hengheng,
Jiang Rongcui,
Tang Yufu,
Ji Yu,
Lu Xiaomei,
Hou Bing,
Deng Weixing,
Huang Wei,
Fan Quli
Publication year - 2017
Publication title -
advanced functional materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.069
H-Index - 322
eISSN - 1616-3028
pISSN - 1616-301X
DOI - 10.1002/adfm.201770264
Subject(s) - materials science , photodynamic therapy , irradiation , conjugated system , photon upconversion , cationic polymerization , in vivo , nanoparticle , photosensitizer , polyelectrolyte , biophysics , nanotechnology , photochemistry , optoelectronics , luminescence , chemistry , polymer , organic chemistry , polymer chemistry , biology , physics , microbiology and biotechnology , nuclear physics , composite material
In article number 1702592 Quli Fan and co‐workers report a photo‐induced charge‐variable cationic conjugated polyelectrolyte brush encapsulating upconversion nanoparticles (UCNP@CCPEB) for siRNA release and collaborative photodynamic therapy under near‐IR light irradiation. With good stability and excellent siRNA‐loading capacity, UCNP@CCPEB exhibits good 1 O 2 production and facilitate siRNA release under 980 nm irradiation, enabling highly effective collaborative tumor therapy in vitro and in vivo.