Drug Delivery: Multifunctional Molecular Beacon Micelles for Intracellular mRNA Imaging and Synergistic Therapy in Multidrug‐Resistant Cancer Cells (Adv. Funct. Mater. 31/2017) | Zendy

Zhang Ruili | Zendy; Gao Shi | Zendy; Wang Zhongliang | Zendy; Han Da | Zendy; Liu Lin | Zendy; Ma Qingjie | Zendy; Tan Weihong | Zendy; Tian Jie | Zendy; Chen Xiaoyuan | Zendy

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Drug Delivery: Multifunctional Molecular Beacon Micelles for Intracellular mRNA Imaging and Synergistic Therapy in Multidrug‐Resistant Cancer Cells (Adv. Funct. Mater. 31/2017)

Author(s) -

Zhang Ruili,

Gao Shi,

Wang Zhongliang,

Han Da,

Liu Lin,

Ma Qingjie,

Tan Weihong,

Tian Jie,

Chen Xiaoyuan

Publication year - 2017

Publication title -

advanced functional materials

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 6.069

H-Index - 322

eISSN - 1616-3028

pISSN - 1616-301X

DOI - 10.1002/adfm.201770179

Subject(s) - micelle , multiple drug resistance , materials science , drug delivery , intracellular , chemotherapeutic drugs , drug , cancer therapy , nanotechnology , cancer cell , cancer , pharmacology , cancer research , biophysics , drug resistance , chemistry , biology , medicine , biochemistry , organic chemistry , aqueous solution , microbiology and biotechnology

An anti‐MDR1 molecular‐beacon‐based micelle nanosystem is demonstrated by Zhongliang Wang, Qingjie Ma, Xiaoyuan Chen, and co‐workers in article number 1701027 . Owing to its ingenious design, the nanosystem is able to successfully administer both a MDR1 gene silencer and a chemotherapeutic agent in a sequential way to produce a synergistic therapeutic effect, enhancing chemotherapeutic efficacy to OVCAR8/ADR cells significantly.

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