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Drug Delivery: A Cooperative Dimensional Strategy for Enhanced Nucleus‐Targeted Delivery of Anticancer Drugs (Adv. Funct. Mater. 24/2017)
Author(s) -
Wang Hebin,
Li Yang,
Bai Hongzhen,
Shen Jie,
Chen Xi,
Ping Yuan,
Tang Guping
Publication year - 2017
Publication title -
advanced functional materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.069
H-Index - 322
eISSN - 1616-3028
pISSN - 1616-301X
DOI - 10.1002/adfm.201770150
Subject(s) - drug delivery , nanotechnology , materials science , drug , anticancer drug , delivery system , pharmacology , medicine
In article number 1700339 , Yuan Ping, Guping Tang, and co‐workers develop a size‐switchable micellar system that can simultaneously target the nucleus and dilate the nucleopore to enhance the intranuclear delivery efficiency of anticancer drugs. This research defines a strategy for the improvement of intranuclear drug delivery capacity, which is expected to augment the overall therapeutic efficacy of a wide range of therapeutics requiring nuclear entry.