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Cancer Therapy: A Drug‐Self‐Gated Mesoporous Antitumor Nanoplatform Based on pH‐Sensitive Dynamic Covalent Bond (Adv. Funct. Mater. 11/2017)
Author(s) -
Zeng Xiaowei,
Liu Gan,
Tao Wei,
Ma Yue,
Zhang Xudong,
He Fan,
Pan Jianming,
Mei Lin,
Pan Guoqing
Publication year - 2017
Publication title -
advanced functional materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.069
H-Index - 322
eISSN - 1616-3028
pISSN - 1616-301X
DOI - 10.1002/adfm.201770065
Subject(s) - nanocarriers , covalent bond , materials science , nanomaterials , nanotechnology , mesoporous material , cancer therapy , drug , anticancer drug , cancer , nanoparticle , organic chemistry , chemistry , pharmacology , medicine , catalysis
In article number 1605985, Xiaowei Zeng, Jianming Pan, Lin Mei, Guoqing Pan, and co‐workers demonstrate a novel pH‐responsive mesoporous nanocarrier that is gated by the delivered drug itself via a reversible covalent bond. The paradigm shift, caused by bypassing the use of auxiliary capping agents, will simplify mesoporous nanomaterials as intelligent drug carriers for therapy of cancer and other diseases.