Premium
Biosensor Array of Interpenetrating Polymer Network with Photonic Film Templated from Reactive Cholesteric Liquid Crystal and Enzyme‐Immobilized Hydrogel Polymer
Author(s) -
Noh KyungGyu,
Park SooYoung
Publication year - 2018
Publication title -
advanced functional materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.069
H-Index - 322
eISSN - 1616-3028
pISSN - 1616-301X
DOI - 10.1002/adfm.201707562
Subject(s) - materials science , uv curing , biosensor , polymer , self healing hydrogels , liquid crystal , interpenetrating polymer network , dopant , polyvinyl alcohol , mesogen , photopolymer , acrylic acid , photomask , chemical engineering , polymer network , photonic crystal , monomer , polymer chemistry , nanotechnology , curing (chemistry) , composite material , doping , optoelectronics , layer (electronics) , liquid crystalline , resist , engineering
A biosensor array is fabricated using an interpenetrating polymer network consisting of photonic film templated from reactive cholesteric liquid crystal (CLC) and enzyme‐immobilized polyacrylic acid (PAA). The solid‐state photonic film on the glass substrate is successfully templated by ultraviolet (UV) curing of the reactive CLC mixture of a reactive mesogen mixture of RMM 727 (from Merck) and a nonreactive chiral dopant of ( S )‐4‐cyano‐4′‐(2‐methylbutyl)biphenyl following the extraction of the chiral dopant. The acrylic acid monomer mixed with a cross‐linker of tri(propylene glycol) diacrylate is infiltrated into the extracted space of the photonic film, and UV‐cured with a photomask to obtain a patterned array‐dot film. The interpenetrated cholesteric liquid crystal/hydrogel polymer network (CLC‐hydrogel‐IPN) array is further functionalized in the individual dots with urease, for a model study of biosensor array applications. The dots of the CLC‐hydrogel‐IPN array respond independently to the urea by a color change with high sensitivity and stability. Thus, the patterned CLC‐hydrogel‐IPN can be used as a new biosensor array for cost‐effective and easy visual detection without any sophisticated instruments.