Hyperammonemia: Liposome‐Supported Peritoneal Dialysis for the Treatment of Hyperammonemia‐Associated Encephalopathy (Adv. Funct. Mater. 46/2016) | Zendy

Agostoni Valentina | Zendy; Lee Soo Hyeon | Zendy; Forster Vincent | Zendy; Kabbaj Meriam | Zendy; Bosoi Cristina R. | Zendy; Tremblay Mélanie | Zendy; Zadory Matthias | Zendy; Rose Christopher F. | Zendy; Leroux JeanChristophe | Zendy

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Hyperammonemia: Liposome‐Supported Peritoneal Dialysis for the Treatment of Hyperammonemia‐Associated Encephalopathy (Adv. Funct. Mater. 46/2016)

Author(s) -

Agostoni Valentina,

Lee Soo Hyeon,

Forster Vincent,

Kabbaj Meriam,

Bosoi Cristina R.,

Tremblay Mélanie,

Zadory Matthias,

Rose Christopher F.,

Leroux JeanChristophe

Publication year - 2016

Publication title -

advanced functional materials

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 6.069

H-Index - 322

eISSN - 1616-3028

pISSN - 1616-301X

DOI - 10.1002/adfm.201670300

Subject(s) - hyperammonemia , peritoneal dialysis , encephalopathy , liposome , materials science , pharmacology , medicine , nanotechnology

On page 8382, J.‐C. Leroux and co‐workers describe a novel approach for treating hyperammonemia induced encephalopathy, based on the peritoneal infusion of giant transmembrane pH‐gradient liposomes bearing an acidic core. These scavenging vesicles allow a safe and effective removal of excess ammonia, outperforming conventional peritoneal dialysis fluids and significantly attenuating brain edema in a rodent model of liver disease.

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