Decellularized Cartilage Microparticles: Dissociated and Reconstituted Cartilage Microparticles in Densified Collagen Induce Local hMSC Differentiation (Adv. Funct. Mater. 30/2016) | Zendy

Novak Tyler | Zendy; Seelbinder Benjamin | Zendy; Twitchell Celina M. | Zendy; VoytikHarbin Sherry L. | Zendy; Neu Corey P. | Zendy

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Decellularized Cartilage Microparticles: Dissociated and Reconstituted Cartilage Microparticles in Densified Collagen Induce Local hMSC Differentiation (Adv. Funct. Mater. 30/2016)

Author(s) -

Novak Tyler,

Seelbinder Benjamin,

Twitchell Celina M.,

VoytikHarbin Sherry L.,

Neu Corey P.

Publication year - 2016

Publication title -

advanced functional materials

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 6.069

H-Index - 322

eISSN - 1616-3028

pISSN - 1616-301X

DOI - 10.1002/adfm.201670195

Subject(s) - cartilage , decellularization , materials science , articular cartilage , biomedical engineering , tissue engineering , nanotechnology , anatomy , pathology , medicine , osteoarthritis , alternative medicine

On page 5427, C. P. Neu and co‐workers report on successfully combining the benefits of native tissue biochemistry/structure with the tunability of reconstituted biomaterials for the formation of clinically relevant tissue composites. Native articular cartilage and reconstituted type I collagen form a moldable ‘cartilage clay’ that can be custom designed to meet the mechanical, biochemical, and geometric needs of a clinical implant; showing the capability to locally differentiate progenitor cells.

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