Nanostructures: Enhanced Differentiation of Human Embryonic Stem Cells Toward Definitive Endoderm on Ultrahigh Aspect Ratio Nanopillars (Adv. Funct. Mater. 6/2016) | Zendy

Rasmussen Camilla Holzmann | Zendy; Reynolds Paul M. | Zendy; Petersen Dorthe Roenn | Zendy; Hansson Mattias | Zendy; McMeeking Robert M. | Zendy; Dufva Martin | Zendy; Gadegaard Nikolaj | Zendy

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Nanostructures: Enhanced Differentiation of Human Embryonic Stem Cells Toward Definitive Endoderm on Ultrahigh Aspect Ratio Nanopillars (Adv. Funct. Mater. 6/2016)

Author(s) -

Rasmussen Camilla Holzmann,

Reynolds Paul M.,

Petersen Dorthe Roenn,

Hansson Mattias,

McMeeking Robert M.,

Dufva Martin,

Gadegaard Nikolaj

Publication year - 2016

Publication title -

advanced functional materials

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 6.069

H-Index - 322

eISSN - 1616-3028

pISSN - 1616-301X

DOI - 10.1002/adfm.201670038

Subject(s) - nanopillar , materials science , nanotechnology , substrate (aquarium) , endoderm , embryonic stem cell , stem cell , nanostructure , microbiology and biotechnology , biology , biochemistry , gene , ecology

N. Gadegaard and co‐workers report on page 815 a nanofabricated thermoplastic substrate with ultra‐high aspect ratio nanopillars. This substrate, formed via injection molding, is used to enhance the differentiation of human embryonic stem cells. The nanostructured surface results in a softer substrate, which mimics the natural extracellular environment.

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