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Photothermal Therapy: Tumor‐Penetrating Nanotherapeutics Loading a Near‐Infrared Probe Inhibit Growth and Metastasis of Breast Cancer (Adv. Funct. Mater. 19/2015)
Author(s) -
He Xinyu,
Bao Xiaoyue,
Cao Haiqiang,
Zhang Zhiwen,
Yin Qi,
Gu Wangwen,
Chen Lingli,
Yu Haijun,
Li Yaping
Publication year - 2015
Publication title -
advanced functional materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.069
H-Index - 322
eISSN - 1616-3028
pISSN - 1616-301X
DOI - 10.1002/adfm.201570131
Subject(s) - photothermal therapy , materials science , breast cancer , metastasis , cancer research , near infrared spectroscopy , cancer , biomedical engineering , nanotechnology , medicine , optics , physics
A deep tumor‐penetrating photothermal nanotherapeutic is developed on page 2831 by Z. Zhang, Y. Li, and co‐workers by loading a near‐infrared (NIR) probe into nanoscaled polymeric carrier for simultaneous inhibition of tumor growth and metastasis. The nanotherapeutic can produce high levels of heat when exposed to NIR light. Moreover, it can penetrate into the deep interior of tumor tissues and be changed into firebombs under NIR light, surprisingly suppressing tumor growth and lung metastases of breast cancer in a single treatment.